EEG and ANI Guided Anesthesia and Quality of Recovery

This study aims to assess whether electroencephalogram (EEG) and nociception level-guided anesthesia can improve quality of recovery after laparoscopic gynecological surgery compared with standard care. Patients will be randomly assigned to either EEG and Analgesia Nociception Index (ANI)-guided anesthesia group (EEG-and-ANI-Guided group) or usual care group (control group). Primary outcome is 15-item Quality of Recovery (QoR-15) score at postoperative day (POD) 1. Secondary outcomes included remifentanil consumption during anesthesia, occurrence of awareness with recall, incidence of undesirable intraoperative movement, emergence time, postoperative pain scores, quality of recovery score at POD 2, and length of hospital stay.

NCT Number	NCT05936671
Lead Sponsor	Gangnam Severance Hospital
Conditions	Laparoscopic Gynecological Surgery
Enrollment	126 participants
Start Date	2023-07-13
Primary Completion	2027-06-19 (estimated)
Study Completion	2027-06-25 (estimated)
Updated on ClinicalTrials.gov	2026-07-23