Biocollection on Peripheral Inflammation

Most psychiatric research is based on the nosographic classifications used in current practice. At present, there is no diagnostic or prognostic biomarker for psychiatric pathologies commonly used in clinical practice. The study hypothesis is that peripheral inflammatory biomarkers could be common to several psychiatric disorders, in particular psychotic disorders (bipolar disorder, schizophreniform disorder, schizophrenia, depressive episode with psychotic features). The aim of this project is to set up a bio-collection of biological samples (peripheral blood samples) with associated phenotypic data (assessment of various symptoms using standardized scales in patients whose blood is sampled). The setting up of this cohort follows on from work carried out on a PsyCourse cohort also using a transdiagnostic approach in psychiatry, in order to be able to collaborate within a European research project.

NCT Number	NCT05934474
Lead Sponsor	Nantes University Hospital Collaborators: CR2TI, INSERM, UMR1064
Conditions	Schizoaffective Disorder, Depressive Type, Bipolar Disorder I, Bipolar Disorder II
Enrollment	50 participants
Start Date	2024-03-19
Primary Completion	2028-03-19 (estimated)
Study Completion	2028-03-19 (estimated)
Updated on ClinicalTrials.gov	2026-07-29