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Results of the Use of Two Stentrievers Simultaneosly Compared With One as a Primary Treatment in Acute Ischemic Stroke

Study acronym: DIVERSO
StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated July 28, 2025 (before its estimated September 1, 2026 completion). Its status may not reflect the trial's current state.

Record History

  1. Minor Re-verified, no change to tracked fieldsv5
  2. Notable Lead sponsor: Hospital Universitario Central de Asturias to Fundación EPIC Trial status: Not Yet Recruiting to Recruiting · Primary completion date: Sep 1, 2024 to Sep 1, 2026 · Start date changed from estimate of Sep 1, 2023 to Mar 14, 2025 · 2 morev4 Show 5 more changesShow less
    • Trial status: Not Yet Recruiting to Recruiting
    • Primary completion date: Sep 1, 2024 to Sep 1, 2026
    • Start date changed from estimate of Sep 1, 2023 to Mar 14, 2025
    • Study sites: 0 to 4
    • Completion date: Sep 1, 2024 to Oct 1, 2026
  3. Minor Secondary endpoints: details revised at 10 of 12 entriesv3
  4. Notable Start date: Jul 1, 2023 to Sep 1, 2023 Primary endpoints revised (2) · Primary and study completion dates: Jul 1, 2024 to Sep 1, 2024 · Secondary endpoints: 14 to 12 · 2 morev2 Show 5 more changesShow less
    • Primary endpoints revised (2)
    • Primary and study completion dates: Jul 1, 2024 to Sep 1, 2024
    • Secondary endpoints: 14 to 12
    • Study description shortened, about 22 words
    • Study title shortened, about 8 words

    See this version in full on ClinicalTrials.gov ↗

  5. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
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Several studies have demonstrated that simultaneous treatment with two stentrievers (STs) as rescue treatment is very effective, with high recanalization rates even in this group of patients where other revascularization techniques have failed. There has been no observed increase in hemorrhagic complications. Recently, a prospective study has been published where treatment with two ST has been shown to be effective and safe if used as a first-choice treatment (not as rescue) with a successful recanalization rate (eTICI 2c/3) after the first pass of 69%. These results have been reinforced after the publication of a randomized study that confirms, in vitro, the superiority of using two ST over one.
Trial Details
NCT Number NCT05930145
Lead Sponsor Fundación EPIC
Conditions Stroke, Thrombectomy, Arterial Occlusive Diseases
Enrollment 200 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov