Determinants of Chronic Inflammatory Skin Disease Trajectories

Although it is well known that the clinical expression and course of chronic inflammatory skin diseases are highly variable, there are insufficient epidemiological data on this, and the factors that determine the manifestation, clinical features and course are also largely unknown. There are currently no reliable markers that could predict or delineate patient subgroups to support patient management. The aim of this project is to identify clinical and molecular factors that correlate with disease, disease subtypes and progression through in-depth long-term clinical characterization of patients with chronic inflammatory skin diseases and examination of individual biomaterials.

NCT Number	NCT05928169
Lead Sponsor	University Hospital Schleswig-Holstein
Conditions	Atopic Dermatitis, Psoriasis, Lichen Planus, Alopecia Areata, Hidradenitis Suppurativa, Prurigo Nodularis, Cutaneous Lupus, Rosacea
Enrollment	1,000 participants
Start Date	2023-05-01
Primary Completion	2032-04-30 (estimated)
Study Completion	2032-12-31 (estimated)
Updated on ClinicalTrials.gov	2025-07-22