Clinical Trial

Study of ALTO-300 in MDD

Name: Study of ALTO-300 in MDD — clinical trial record (NCT05922878)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Recruiting Phase 2

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Summary

The purpose of this study is to determine efficacy differences between ALTO-300 and placebo, used adjunctively to an antidepressant, related to patient characteristics.

Protocol Amendment History 11 amendments

This ClinicalTrials.gov record has been amended 11 times since 2023-06-19; most recent amendment 2025-07-21.

Trial Details

NCT Number	NCT05922878
Lead Sponsor	Alto Neuroscience
Conditions	Major Depressive Disorder
Enrollment	321 participants
Start Date	2023-06-08
Primary Completion	2026-12 (estimated)
Study Completion	2026-12 (estimated)
Updated on ClinicalTrials.gov	2025-07-24