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Efficacy of NA Combined With PEG-IFN-α2b in the Continuous Versus Pulsed Treatment of Patients With Chronic Hepatitis B

Study acronym: EPCP
StatusRecruiting
PhaseEarly Phase 1
Started
View on ClinicalTrials.gov ↗

Record History

  1. Study First Submitted
Previous studies have shown that there are alterations in the number and affinity of interferon receptors during interferon therapy and that such alterations recover to varying degrees some time after the end of treatment. It can be conjectured that the rest period of pulsed therapy facilitates the recovery of type I interferon receptors and thus the next round of IFN therapy compared to a continuous regimen of interferon.
Trial Details
NCT Number NCT05922306
Lead Sponsor Anhui Medical University
Collaborators: The First Affiliated Hospital, University of Science and Technology of China, The Second Hospital of Anhui Medical University, Chaohu Hospital of Anhui Medical University, The First Affiliated Hospital of Bengbu Medical University
Conditions
(from sponsor)		 Hepatitis B, Chronic
Related terms Hepatitis B, Chronic
Enrollment 1,084 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov