Short- and Medium-term Evaluation of Mastoid Filling Using Bioactive Glass"

Adult patients referred to the ENT surgery department of the Hospices Civils de Lyon with cholesteatoma that had never been operated on. All patients will benefit from surgical management for cholesteatoma initially in the operating room under general anesthesia. The surgical technique (closed technique) is the reference technique for the management of cholesteatoma in adults. It involves a cartilaginous removal to reconstruct the attical region. Then a filling material is used to fill the mastoid (GlassBONE™ or Bonalive™), and above all to stabilize the cartilaginous fragment to prevent a recurrence.

NCT Number	NCT05921643
Lead Sponsor	Centre Hospitalier Intercommunal Creteil
Conditions	Cholesteatoma
Enrollment	70 participants
Start Date	2023-09-29
Primary Completion	2028-03 (estimated)
Study Completion	2030-04 (estimated)
Updated on ClinicalTrials.gov	2026-06-16