Clinical Trial

Ultra-hypofractionated for Whole Breast Irradiation (WBI) Compared to Partial Breast Irradiation (PBI)

Recruiting Phase 2
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Record status
This record was last updated July 3, 2023 (before its estimated May 31, 2026 completion). Its status may not reflect the trial's current state.
Summary
Female patients undergoing surgical treatment for early breast cancer and meeting the inclusion criteria for adjuvant breast radiotherapy were randomized into two groups. One group will receive adjuvant whole-breast radiotherapy in ultra-hypofractionated regimen of 26 Gy in 5 fractions. In contrast, the other group will receive partial breast irradiation with a dose of 26Gy in 5 fractions. The study's objective is to compare the effects of both breast radiotherapy protocols in terms of locoregional disease control and survival and to compare the adverse effects of radiotherapy between the two protocols. To determine if there is a correlation between different parameters and the efficacy and degree of toxicity for both protocols.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2023-06-19.
Trial Details
NCT Number NCT05914831
Lead Sponsor Oncology Institute of Vojvodina
Conditions Breast Cancer Female
Enrollment 100 participants
Start Date 2023-06-01
Primary Completion 2026-05-31 (estimated)
Study Completion 2033-05-31 (estimated)
Updated on ClinicalTrials.gov 2023-07-03