The Effects of an Obesogenic Lifestyle in Recreationally Active, Young Adults

This clinical trial aims to learn about the alterations in insulin resistance and metabolic flexibility following a transition to an obesogenic lifestyle in fit young men and women. The main questions it aims to answer are: 1. Does adding excess carbohydrates when transitioning to a sedentary lifestyle promote insulin resistance and impaired 24hr glucose regulation in healthy men and women? 2. Does adding excess carbohydrates when transitioning to a sedentary lifestyle lower the body's ability to break down fats and carbohydrates in healthy men and women? 3. Does the added physical activity blunt shifts in carbohydrate and fat oxidation in healthy men and women?

NCT Number	NCT05912348
Lead Sponsor	University of New Hampshire
Conditions	Insulin Resistance, Impaired Glucose Tolerance, Obesity, Metabolic Disturbance
Enrollment	45 participants
Start Date	2023-02-08
Primary Completion	2026-09-30 (estimated)
Study Completion	2026-09-30 (estimated)
Updated on ClinicalTrials.gov	2024-07-17