Subpectoral Bupivacaine for Pain Management in Adolescent Reduction Mammaplasty

The main question this randomized control trial aims to answer is: • Is the use of intraoperative subpectoral bupivacaine associated with decreased post-operative pain in adolescent patients who undergo bilateral reduction mammaplasty Participants will be randomized into the study group that intraoperatively receives 30cc of subpectoral bupivacaine injections or into the control group that intraoperatively receives 30cc of injectable saline subpectorally. All participants will keep a pain log and pain medication log at home for the first week following surgery. Researchers will compare to see if patients who receive subpectoral bupivacaine have lower pain scores in the PACU, and lower use of narcotics post-operatively when compared to the control group who receive injectable saline.

NCT Number	NCT05898087
Lead Sponsor	Connecticut Children's Medical Center
Conditions	Macromastia, Post-operative Pain
Enrollment	52 participants
Start Date	2022-04-01
Primary Completion	2026-05-08 (estimated)
Study Completion	2026-05-08 (estimated)
Updated on ClinicalTrials.gov	2026-07-31