Gfree - For Improved Blood Sugar and Reduced Inflammation.

The goal of this clinical trial is to reduce inflammation and improve glycemic control in healthy volunteers, parents, as well as children, adolescents and adults with or without diabetes. The main questions it aims to answer are: • does a reduction wheat gluten improve glycemic control and/or inflammatory biomarkers • does a reduction in certain amino acids (which is most common in wheat gluten) improve glycemic control and/or inflammatory biomarkers • can we identify individuals with an inflammatory response, which leads to poor glycemic control. Participants will eat gluten-free products as well as similar products containing gluten. They will also eat gluten together with probiotics to see if an effect of gluten can be reduced. Researchers will compare everyone with themselves (cross-over design) and if possible individuals with and without diabetes.

NCT Number	NCT05894746
Lead Sponsor	Göteborg University Collaborators: University of Skövde, Sahlgrenska University Hospital, Ekhaga foundation
Conditions	Diabetes, Celiac Disease, Autoimmunity, Metabolic Disease
Enrollment	60 participants
Start Date	2023-05-04
Primary Completion	2025-12-01 (estimated)
Study Completion	2030-12-31 (estimated)
Updated on ClinicalTrials.gov	2024-10-15