Total Neoadjuvant Treatment Combined With Adaptive Radiotherapy for Rectal Cancer

Diarrhea was the most frequently reported severe adverse event in the treatment regime of pre-operative sequential short-course radiotherapy followed by chemotherapy (so called total neo-adjuvant treatment). This study therefore investigates the benefit of on-couch adaptation for locally advanced rectal cancer patients undergoing this treatment regime.

NCT Number	NCT05883800
Lead Sponsor	Haukeland University Hospital
Conditions	Rectal Cancer
Enrollment	61 participants
Start Date	2023-06-22
Primary Completion	2026-12-31 (estimated)
Study Completion	2031-12-31 (estimated)
Updated on ClinicalTrials.gov	2024-03-19