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Mechanisms Of Disease Progression in Aortic Stenosis - the MODAS Study

StatusRecruiting
PhaseNot specified
Started2023-07-01
View on ClinicalTrials.gov ↗
Record status
This record was last updated June 30, 2026 (before its estimated July 2026 completion). Its status may not reflect the trial's current state.

Amendment history

2026-06-26
Not Yet Recruiting→Recruiting Study Identification, Study Status, Contacts/Locations v1
Trial statusNot Yet Recruiting→Recruiting
Study sitesdetails revised at 3 of 3 sites
Study title-19 characters
Biomarkers and Mechanisms ofOf Disease Progression and Outcome ofin Aortic Stenosis in- Humansthe MODAS Study
2023-05-05
Original filing
Biomarkers and mechanisms in the progression of aortic valve stenosis are sometimes not sufficiently understood. The current project will take into account image morphological and immunological aspects that predict the development of hemodynamically relevant aortic valve stenosis in order to identify high-risk patients and to develop further therapeutic options.
Trial Details
NCT Number NCT05851209
Lead Sponsor Heinrich-Heine University, Duesseldorf
Collaborators: German Research Foundation, University of Bonn, University Cologne, Collaborative Research Center
Conditions Aortic Stenosis, Imaging, Pathogenesis, Disease Progression, Aortic Valve Calcification, Genetics
Enrollment 938 participants
Start Date 2023-07-01
Primary Completion 2026-07 (estimated)
Study Completion 2031-07 (estimated)
Updated on ClinicalTrials.gov 2026-06-30