Clinical Trial

The Viability Control of Human Endothelial Cells Before Keratoplasty (V-CHECK) Study

Study acronym: V-CHECK
Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated October 2, 2025 (before its estimated March 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
The purpose of this international cohort study is to validate a new method for preoperative assessment of endothelial viability in donor corneal tissues for transplantation, and to correlate endothelial health as assessed by the surgical team to functional and structural long-term outcomes in the cohort of patients receiving them.
Protocol Amendment History 4 amendments
This ClinicalTrials.gov record has been amended 4 times since 2023-04-27; most recent amendment 2025-09-29.
Status change: Not Yet Recruiting → Recruiting 2024-02-03
Trial Details
NCT Number NCT05847387
Lead Sponsor Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Conditions Corneal Transplant Failure, Corneal Endothelial Cell Loss
Enrollment 135 participants
Start Date 2023-12-01
Primary Completion 2026-03-30 (estimated)
Study Completion 2026-09-30 (estimated)
Updated on ClinicalTrials.gov 2025-10-02