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Patient-centred Deprescribing of Psychotropic, Sedative and Anticholinergic Medication in Elderly Patients With Polypharmacy

Study acronym: PARTNER
StatusRecruiting
PhaseNot applicable
Started
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Record status
This record was last updated May 4, 2025 (before its estimated April 2026 completion). Its status may not reflect the trial's current state.

Record History

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  1. Primary completion date: Jul 2024 to Apr 2026
    • Study completion date: Dec 2024 to Oct 2026
    v3
  2. Secondary endpoints revised (11)
    • Study title shortened, about 3 words
    v2
  3. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The PARTNER study is a multicentre, two-arm, pragmatic cluster-randomised trial evaluating the impact of a focused and patient-centred cooperation between general practitioners (GPs) and community pharmacists (PARTNER intervention) on reductions in the use of psychotropic, sedative and anticholinergic potentially inappropriate medication (PSA-PIM) compared to a control intervention. The PARTNER intervention comprises (1) education for health care professionals, (2) an interprofessional workshop and case conference, (3) a pharmacy visit with brown bag/medication review and patient empowerment, (4) GP practice visit with shared decision making. The control intervention only comprises a pharmacy visit with brown bag review.
Trial Details
NCT Number NCT05842928
Lead Sponsor Ludwig-Maximilians - University of Munich
Collaborators: Bielefeld University, University of Witten/Herdecke, University Hospital Heidelberg, University Hospital Regensburg, Institute for Applied Quality Improvement and Research in Health Care, Techniker Krankenkasse, Federal Joint Committee
Conditions
(from sponsor)		 Deprescriptions, Antidepressive Agents, Antipsychotic Agents, Analgesics, Opioid, Hypnotics and Sedatives, Cholinergic Antagonists
Enrollment 352 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov