Clinical Trial

Patient-centred Deprescribing of Psychotropic, Sedative and Anticholinergic Medication in Elderly Patients With Polypharmacy

Study acronym: PARTNER
Recruiting
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Record status
This record was last updated May 4, 2025 (before its estimated April 2026 completion). Its status may not reflect the trial's current state.
Summary
The PARTNER study is a multicentre, two-arm, pragmatic cluster-randomised trial evaluating the impact of a focused and patient-centred cooperation between general practitioners (GPs) and community pharmacists (PARTNER intervention) on reductions in the use of psychotropic, sedative and anticholinergic potentially inappropriate medication (PSA-PIM) compared to a control intervention. The PARTNER intervention comprises (1) education for health care professionals, (2) an interprofessional workshop and case conference, (3) a pharmacy visit with brown bag/medication review and patient empowerment, (4) GP practice visit with shared decision making. The control intervention only comprises a pharmacy visit with brown bag review.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2023-04-24; most recent amendment 2025-04-30.
Trial Details
NCT Number NCT05842928
Lead Sponsor Ludwig-Maximilians - University of Munich
Collaborators: Bielefeld University, University of Witten/Herdecke, University Hospital Heidelberg, University Hospital Regensburg, Institute for Applied Quality Improvement and Research in Health Care, Techniker Krankenkasse, Federal Joint Committee
Conditions Deprescriptions, Antidepressive Agents, Antipsychotic Agents, Analgesics, Opioid, Hypnotics and Sedatives, Cholinergic Antagonists
Enrollment 352 participants
Start Date 2023-03-25
Primary Completion 2026-04 (estimated)
Study Completion 2026-10 (estimated)
Updated on ClinicalTrials.gov 2025-05-04