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Magnesium Prophylaxis for the Prevention of New-Onset Atrial Fibrillation in Critically Ill Patients

Study acronym: ATOMIC
StatusRecruiting
PhasePhase 4
Started2023-08-20
View on ClinicalTrials.gov ↗
A double-blind, multi-centre, randomized, placebo-controlled, feasibility pilot trial in the prevention of new onset atrial fibrillation of critically ill patients admitted to an ICU.

Amendment record

Amended 3 times since 2023-04-12; most recent filed 2025-09-17. Every amendment is listed below.

Dates here are the day the sponsor filed the amendment, not the day ClinicalTrials.gov published it. Version history last read from ClinicalTrials.gov on 2026-08-30.

2025-09-17
Amendment Study Status, Sponsor/Collaborators, Study Design, Outcome Measures, Eligibility, Contacts/Locations, IPDSharing v3
2024-11-12
Amendment Study Status, Sponsor/Collaborators, Oversight, Eligibility, Contacts/Locations v2
2023-11-14
Amendment Not Yet Recruiting→Recruiting Study Status, Outcome Measures, Contacts/Locations v1
2023-04-12
Original filing
Trial Details
NCT Number NCT05829317
Lead Sponsor Dr. Stephanie Sibley
Collaborators: Southeastern Ontario Academic Medical Organization (SEAMO), Canadian Institutes of Health Research (CIHR)
Conditions Critical Illness, New Onset Atrial Fibrillation
Enrollment 200 participants
Start Date 2023-08-20
Primary Completion 2028-03-01 (estimated)
Study Completion 2028-07-01 (estimated)
Updated on ClinicalTrials.gov 2025-09-22