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GAE Using Embosphere Microspheres vs Corticosteroid Injections for Treatment of Symptomatic Knee OA (MOTION)

Study acronym: MOTION
StatusActive, Not Recruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated October 24, 2025 (before its estimated April 2026 completion). Its status may not reflect the trial's current state.

Record History

See every version on ClinicalTrials.gov ↗

  1. Trial status: Recruiting to Active, Not Recruiting
    • Study sites: 23 to 27
    v11
  2. Re-verified, no change to tracked fieldsv10
  3. Site details revised at 23 of 23 sitesv9
  4. Study sites: 22 to 23v8
  5. Study sites: 23 to 22
    • Eligibility criteria expanded, about 2 words
    v7
Show 5 earlier versionsHide 5 earlier versions
  1. Study description revised
    • Study sites revised (23)
    • Study title expanded, about 1 word
    v6
  2. Start date changed from estimate of Jan 2024 to Jan 16, 2024v5
  3. Trial status: Not Yet Recruiting to Recruiting
    • Site details revised at 23 of 23 sites
    v4
  4. Enrollment target: 270 to 264v3 Show 5 more changesShow less
    • Study sites: 0 to 23
    • Interventions: Corticosteroid injection (Drug), EmboSphere Microspheres (Device) to Corticosteroid injection (Drug), Embosphere Microspheres (Device)
    • Secondary endpoints: details revised at 1 of 2 entries
    • Study description expanded, about 22 words
    • Eligibility criteria shortened, about 3 words
  5. Eligibility criteria shortened, about 598 wordsv2
  1. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This multicenter, prospective, interventional trial is designed to assess the outcome of subjects with symptomatic knee osteoarthritis (OA) that are randomized to treatment with either genicular artery embolization (GAE) using Embosphere Microspheres or steroid injection over a period of 24 months.
Trial Details
NCT Number NCT05818150
Lead Sponsor Merit Medical Systems, Inc.
Conditions
(from sponsor)		 Knee Osteoarthritis
Related terms Osteoarthritis, Knee
Enrollment 264 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov