Maternal Stress and Blood Sugar Metabolization

During pregnancy, gestational diabetes increases the risk of complications and adverse outcomes for mother and child, however about 50% of gestational diabetes cases are diagnosed without a known risk factor present. This project uses both a large sample retrospective study, and a prospective study to help us understand the mechanisms by which mental health and stress impact glucose metabolization during pregnancy and delineate their contribution to gestational diabetes and racial disparities. The investigators expect, to improve the ability to identify women at risk, and advance options for preventative care and treatment, decreasing the impact of gestational diabetes and related complications.

NCT Number	NCT05798377
Lead Sponsor	Sanford Health Collaborators: National Institute of General Medical Sciences (NIGMS)
Conditions	Pregnancy
Enrollment	150 participants
Start Date	2023-05-31
Primary Completion	2025-09-15 (estimated)
Study Completion	2027-01-31 (estimated)
Updated on ClinicalTrials.gov	2026-03-20