Clinical Trial

Behavioral Treatment and Memantine in Body Focused Repetitive Behaviors

Active, Not Recruiting Phase 2/3
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Summary
The goal of the proposed study is to compare the efficacy of behavioral treatment (BT) to memantine, a psychopharmacological agent, for BFRBs. 28 subjects with trichotillomania (TTM) or skin picking disorder (SPD) will receive 8 weeks of memantine treatment, followed by 8 weeks of comprehensive behavioral therapy (ComB) treatment. The hypothesis to be tested is that behavioral therapy will be associated with superior clinical outcomes as compared to memantine. A second hypothesis is that both memantine and behavioral therapy will demonstrate improvement from baseline to the respective posttreatment assessment.
Trial Details
NCT Number NCT05796752
Lead Sponsor University of Chicago
Conditions Skin-Picking, Trichotillomania (Hair-Pulling Disorder)
Enrollment 26 participants
Start Date 2023-08-02
Primary Completion 2026-06 (estimated)
Study Completion 2026-06 (estimated)
Updated on ClinicalTrials.gov 2026-06-11