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Prolonged Progesterone to Prevent Preterm Birth From IVF - ET

StatusRecruiting
PhasePhase 4
Started2023-04-01
View on ClinicalTrials.gov ↗

Amendment history

2026-06-08
minor
Study Status v2
Start date2026-04-30→2023-04-01
2026-06-05
notable
Not Yet Recruiting→Recruiting Study Status, Sponsor/Collaborators, Study Description, Outcome Measures, Eligibility, Contacts/Locations v1
Trial statusNot Yet Recruiting→Recruiting
Primary completion date2025-02-28→2029-04-30
Completion date2025-02-28→2029-04-30
Start dateestimated 2023-04-01→confirmed 2026-04-30
Eligibility criteria-680 characters
Inclusion Criteriacriteria are: 1. age 20-40 years; old 2. metmeeting the conditionsindications offor assisted reproductive technology (ART) and underwent IVFundergoing fresh embryo transplantationtransfer 3.with Singletonin vitro fertilization (IVF); singleton pregnancy 4. Patients volunteered; and signedwillingness to participate and provide written informed consent prior to the trial. Exclusion Criteriacriteria are: 1. age >40 years; old 2. Historyhistory of second-trimester miscarriage or cervical insufficiency in the second trimester 3. Abnormal; ovarian functiondysfunction or relevant su [...] [...]
Secondary endpoints+31 characters
live birth rate cervical length
Study description+846 characters
ParticipantInclusion criteria were: age 20-40 years; old,indication IVFfor assisted reproductive technology (ART) with fresh embryo transplantation,transfer via in vitro fertilization (IVF); singleton pregnancy; and willingness to participate and provide written informed consent. Exclusion criteria were: age >40 years; history of second-trimester miscarriage or cervical insufficiency; ovarian dysfunction or prior ovarian surgery; uterine malformation; conditions associated with abnormal uterine cavity mor [...] , blood/urineor HCGhistory (+)of cervical surgery; refractory vaginitis; multiple pregnanc [...] [...]
2023-03-15
minor
Original filing
To investigate the incidence of preterm birth in IVF fresh embryo transplantation cycle patients after prolonged vaginal progesterone treatment
Trial Details
NCT Number NCT05787509
Lead Sponsor Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Conditions Preterm Birth
Enrollment 100 participants
Start Date 2023-04-01
Primary Completion 2029-04-30 (estimated)
Study Completion 2029-04-30 (estimated)
Updated on ClinicalTrials.gov 2026-06-11