Early Neurophysiological Markers of Language Impairments

The present project aims at identifying very early electrophysiological risk markers for language impairments. The long-term goals of the study include the characterization of learning developmental trajectories in children at high risk for language impairments. In this project, all the infants of the Medea BabyLab cohort are followed-up until school age. Since these infants have complete information on early electrophysiological markers, the final goal of the project is the characterization of their learning developmental trajectories and the construction of a multi-factor prognostic model that includes the neurophysiological processes underlying basic-level skills as potential biomarkers for predicting later reading and spelling skills.

NCT Number	NCT05767242
Lead Sponsor	IRCCS Eugenio Medea
Conditions	Development, Infant, Development, Language, Developmental Language Disorder, Learning Disabilities
Enrollment	100 participants
Start Date	2022-02-21
Primary Completion	2026-12-31 (estimated)
Study Completion	2026-12-31 (estimated)
Updated on ClinicalTrials.gov	2025-02-05