Fibrosis in Chronic and Delayed Myocardial Infarction

In this study the investigators aim to examine the role that fibrosis plays in heart conditions such as aortic stenosis , chemotherapy-induced cardiotoxicity and carcinoid syndrome . Fibrosis is a common final result following any injury to the heart muscle and the investigators aim to identify this process early and in its active state. This will be examined by using a radiotracer 68Ga-FAPI or 18F-AlF-FAPI and PET-MRI or PET-CT.

NCT Number	NCT05756608
Lead Sponsor	University of Edinburgh
Conditions	Aortic Stenosis, Chemotherapy Induced Systolic Dysfunction, Carcinoid Syndrome
Enrollment	50 participants
Start Date	2022-11-10
Primary Completion	2026-07-23 (estimated)
Study Completion	2026-07-23 (estimated)
Updated on ClinicalTrials.gov	2026-08-12