Clinical Trial

Optic Nerve Sheath Ultrasound in Giant Cell Arteritis

Study acronym: SONIC-GCA
Recruiting
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Summary
The Sonographic Assessment of the Optic Nerve Sheath in Giant Cell Arteritis (SONIC-GCA) study will evaluate the performance of the optic nerve sheath diameter (ONSD), measured via ultrasound, to diagnose and monitor GCA. SONIC-GCA builds upon our previous pilot studies and will answer the following questions: 1. What is the performance of ONSD to identify patients with new-onset, active GCA? 2. Is ONSD useful for monitoring GCA relapses during follow-up? 3. What is the intra- and interobserver reliability of ONSD measurements? 4. Does ONSD differ between patients with and without GCA-related retinal findings?
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2023-02-18; most recent amendment 2025-08-02.
Status change: Not Yet Recruiting → Recruiting 2025-08-02
Trial Details
NCT Number NCT05749094
Lead Sponsor Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Collaborators: McGill University Health Centre/Research Institute of the McGill University Health Centre, Ciusss de L'Est de l'Île de Montréal, Estrie University Integrated Health and Social Services Center - University Hospital of Sherbrooke, Mount Sinai Hospital, Canada, St. Joseph's Health Care London, Ottawa Hospital Research Institute
Conditions Giant Cell Arteritis, Anterior Ischemic Optic Neuropathy, Optic Neuropathy, Ischemic
Enrollment 285 participants
Start Date 2025-08
Primary Completion 2027-12 (estimated)
Study Completion 2029-03 (estimated)
Updated on ClinicalTrials.gov 2025-08-07