Clinical Trial

INflammation and Small Vessel Disease Study

Study acronym: INSVD
Unknown
View on ClinicalTrials.gov →
Record status
This record was last updated February 27, 2023 (before its estimated July 31, 2026 completion). Its status may not reflect the trial's current state.
Summary
A prospective observational cohort study in patients with cerebral small vessel disease deterring whether changes in systemic inflammation predict brain white matter damage measured using MRI and cognitive decline. This is a study funded by a joint BHF-Dutch Heart Foundation research grant and will be conducted in both Cambridge UK and Nijmegen Netherlands with 100 of the 200 total participants recruited at each site, and data from both sites analysed together.
Protocol Amendment History 1 change
critical Trial status changed: Recruiting → Unknown 2026-08-09
Trial Details
NCT Number NCT05746221
Lead Sponsor University of Cambridge
Collaborators: Radboud University Medical Center, Wolfson Brain Imaging Centre
Conditions Cerebral Small Vessel Diseases, Inflammation, Stroke
Enrollment 200 participants
Start Date 2022-08-10
Primary Completion 2026-07-31 (estimated)
Study Completion 2026-07-31 (estimated)
Updated on ClinicalTrials.gov 2023-02-27