Clinical Trial

EUS-RFA Versus Surgery for Pancreatic Insulinoma (ERASIN-RCT)

Study acronym: ERASIN-RCT
Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
The goal of this muticentre randomized controlled trial is to compare endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) with surgery for treatment of pancreatic insulinoma. The main questions it aims to answer are: 1) What is the safest treatment? 2) Is efficacy comparable? Patients will be randomized to undergo EUS-RFA or surgical resection. Researchers will compare the rate of adverse events and the clinical efficacy after the two treatments to see if EUS-RFA result safer and effective compare with surgery.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2023-02-09; most recent amendment 2026-01-11.
Status change: Recruiting → Active, Not Recruiting 2026-01-11
Status change: Not Yet Recruiting → Recruiting 2023-03-17
Trial Details
NCT Number NCT05735912
Lead Sponsor Azienda Ospedaliera Universitaria Integrata Verona
Conditions Pancreatic Insulinoma
Enrollment 60 participants
Start Date 2023-03-01
Primary Completion 2028-10-31 (estimated)
Study Completion 2028-10-31 (estimated)
Updated on ClinicalTrials.gov 2026-01-13