Clinical Trial

A Study to Compare Two Rehabilitation Protocols for Knee Osteoarthritis

Active, Not Recruiting
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Summary
The aim of this randomized controlled study is to investigate whether the implementation of Blood Flow Restriction, in which the de-loading factor is delivered by the combined progressive de-loaded walking to running activity on an antigravity treadmill (treatment group), is more effective than the same antigravity protocol alone (control group). Participants will be divided as follows: Intervention group: anti-gravity treadmill combined with blood flow restriction Control group: anti-gravity treadmill Both groups will also undergo a standardized knee Osteoarthritis management through an aerobic and strength program.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2023-02-14; most recent amendment 2026-03-03.
Status change: Recruiting → Active, Not Recruiting 2026-03-03
Status change: Not Yet Recruiting → Recruiting 2023-08-04
Trial Details
NCT Number NCT05728827
Lead Sponsor Ente Ospedaliero Cantonale, Bellinzona
Conditions Knee Osteoarthritis
Enrollment 70 participants
Start Date 2023-03-15
Primary Completion 2026-09 (estimated)
Study Completion 2026-09 (estimated)
Updated on ClinicalTrials.gov 2026-03-05