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NCT05726136 · ClinicalTrials.gov record · last posted 2026-04-30

Fluid Challenge and Plasma Volume, During Surgery

Study acronym: FC-VE
StatusRecruiting
PhasePhase 4
Started2023-10-23
View on ClinicalTrials.gov ↗
from the ClinicalTrials.gov record
A short bolus infusion of fluid, called "fluid challenge" is commonly recommended for fluid treatment during longer surgery. However a prolonged increase of the blood volume is a prerequisite to recommend the technique. The purpose with the study is to examine the plasma expanding effect of three different fluid challenge strategies (acetated Ringers 4 ml/kg body weight, albumin 5% 4 ml/kg body weight or albumin 20% 1 ml/kg body weight), using hemoglobin as a dilution indicator.

Amendment record 2 amendments on the ClinicalTrials.gov record

This ClinicalTrials.gov record has been amended 2 times since 2023-02-09; most recent amendment 2026-04-24. DataLookout shows field-level changes from the day a trial enters its daily monitoring; earlier amendments are counted here from the ClinicalTrials.gov version history. See every version on ClinicalTrials.gov ↗

2024-03-14
Status change Not Yet Recruiting→Recruitingv1
Trial Details
NCT Number NCT05726136
Lead Sponsor Joachim Zdolsek
Conditions Colorectal Cancer, Urologic Cancer, Gynecologic Cancer, Colorectal Disorders, Benign Neoplasm
Enrollment 60 participants
Start Date 2023-10-23
Primary Completion 2026-10-31 (estimated)
Study Completion 2026-10-31 (estimated)
Updated on ClinicalTrials.gov 2026-04-30