Clinical Trial

BENTO - Bronchoscopic Lung Volume Reduction in Severe Emphysema Using Thermoablation

Recruiting
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Record status
This record was last updated August 24, 2025 (before its estimated April 25, 2026 completion). Its status may not reflect the trial's current state.
Summary
Prospective, 2-arm, randomised (2:1), multicentre, open-label clinical trial in patients with severe emphysema. The intervention arm will be treated with Bronchoscopic lung volume reduction in severe emphysema using thermoablation.The interventional treatment (bronchoscopic lung volume reduction) is compared with the usual conservative standard therapy (GOLD guidelines).
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2023-02-06; most recent amendment 2025-08-19.
Status change: Not Yet Recruiting → Recruiting 2024-12-05
Trial Details
NCT Number NCT05717192
Lead Sponsor IHF GmbH - Institut für Herzinfarktforschung
Conditions Emphysema or Chronic Obstructive Pulmonary Disease
Enrollment 224 participants
Start Date 2024-04-24
Primary Completion 2026-04-25 (estimated)
Study Completion 2027-12-01 (estimated)
Updated on ClinicalTrials.gov 2025-08-24