Clinical Trial

How Simplified Language Affects Comprehension and Learning in Young Autistic Children

Study acronym: PALS
Recruiting
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Summary
The long-term study goal is to experimentally evaluate the components (and likely active ingredients) of early language interventions for young children with ASD. The overall objective is to determine how single-word and telegraphic simplification affects real-time language processing and word learning in young children with ASD (relative to full, grammatical utterances). The proposed project will investigate three specific aims: 1) Determine how single-word and telegraphic simplification affects language processing. 2) Determine how single-word and telegraphic simplification affects word learning. 3) Evaluate child characteristics that may moderate the effects of linguistic simplification on language processing and word learning. Aim 1 will test the hypothesis that children with ASD will process full, grammatical utterances faster and more accurately than single-word or telegraphic utterances. Aim 2 will test the hypothesis that full, grammatical utterances will support word learning better than telegraphic or single-word utterances. Aim 3 will test the hypothesis that language and cognitive skills significantly moderate the effects of linguistic simplification on language processing and word learning in young children with ASD.
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2023-01-31; most recent amendment 2026-06-11.
Status change: Not Yet Recruiting → Recruiting 2023-04-24
Trial Details
NCT Number NCT05707923
Lead Sponsor Michigan State University
Collaborators: National Institute on Deafness and Other Communication Disorders (NIDCD)
Conditions Autism Spectrum Disorder
Enrollment 104 participants
Start Date 2023-06-01
Primary Completion 2027-05-31 (estimated)
Study Completion 2027-05-31 (estimated)
Updated on ClinicalTrials.gov 2026-06-15