Clinical Trial

Surgical Treatment of Peri-implantitis Using a Bone Substitute With or Without a Resorbable Collagen Membrane

Enrolling by Invitation
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Summary
The objective of the present randomized clinical trial will be to compare two surgical methods of treating peri-implantitis. This study will determine if surgical debridement of peri-implantitis bone defects, including air powder abrasive (APA) decontamination of implant surfaces, in combination with the placement of a bone graft, differs in treatment outcomes compared to placing the same bone graft material with a resorbable collagen membrane placed over the bone graft.
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2023-01-16; most recent amendment 2026-02-12.
Status change: Recruiting → Enrolling by Invitation 2023-04-16
Trial Details
NCT Number NCT05699343
Lead Sponsor Andrea Ravida
Collaborators: SigmaGraft Inc.
Conditions Peri-Implantitis, Surgery
Enrollment 52 participants
Start Date 2023-01-30
Primary Completion 2028-01 (estimated)
Study Completion 2028-12 (estimated)
Updated on ClinicalTrials.gov 2026-02-17