Clinical Trial

Engagement in CHildhood-Onset Systemic Lupus

Study acronym: ECHOS
Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
The goal of this observational (Aim 1) and pilot study (Aim 2) is to better understand how depression symptoms may contribute to how well adolescent and young adults with lupus follow-up with their lupus clinical care. The main questions the overall study attempts to answer are: 1. Whether anhedonia (a core symptom of depression) predicts disengagement in care 2. Whether a patient-tailored mobile health application built to improve both engagement in care and depression symptoms will be feasible and acceptable to adolescents and young adults with lupus. Participants with systemic lupus, ages 15-24 from the Bronx, New York will be asked to complete questionnaires; some will be asked to participate in focus groups to help adapt the mobile health app; participants will also be invited to join a pilot study to try the mobile health app for 6 months and answer questionnaires to document the experience.
Protocol Amendment History 3 changes
critical Trial status changed: Enrolling by Invitation → Active, Not Recruiting 2026-08-01
notable Enrollment increased: 40 -> 48 participants 2026-08-01
notable Primary completion pushed: 2026-12 -> 2027-02 2026-08-01
Trial Details
NCT Number NCT05693571
Lead Sponsor Montefiore Medical Center
Collaborators: Childhood Arthritis and Rheumatology Research Alliance, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Conditions Lupus Erythematosus, Systemic, Depression
Enrollment 48 participants
Start Date 2024-12-05
Primary Completion 2027-02 (estimated)
Study Completion 2027-02 (estimated)
Updated on ClinicalTrials.gov 2026-07-31