Electroclinical Correlates in Essential Tremor

Essential tremor (ET) is a neurological disorder that affects nearly 0.9% of the world's population. High-frequency Deep Brain Stimulation (DBS) of the ventral-intermediate nuclei of the thalamus (VIM) has been proven as an effective second-line treatment for severe forms of ET. The arrival on the market of the PERCEPT™ (new stimulator/recorder, Medtronic, Minneapolis, USA) now allows, in addition to the stimulation delivery, the recording of intracerebral activity at a distance from surgery, in a non-invasive way and in ecological condition at home. Investigators aim at recording the variations of thalamic Local Field Potentials (LFP) oscillations, in ecological condition, during rest and movement, with and without deep brain stimulation, once a week, between M3 and M6 post surgery.

NCT Number	NCT05671848
Lead Sponsor	University Hospital, Bordeaux Collaborators: MINDig
Conditions	Essential Tremor
Enrollment	10 participants
Start Date	2023-05-03
Primary Completion	2025-07-16 (estimated)
Study Completion	2025-11-26 (estimated)
Updated on ClinicalTrials.gov	2026-08-07