Clinical Trial

Low-CArbohydrate Diet and SGLT2-INhibitOr to Achieve Moderate Ketosis in Healthy Volunteers

Study acronym: CASINO
Active, Not Recruiting Phase 1
View on ClinicalTrials.gov →
Summary
The purpose of this study is to help us better understand how plasma ketones respond to a low-carb diet when combined with an SGLT2 inhibitor.
Protocol Amendment History 8 amendments
This ClinicalTrials.gov record has been amended 8 times since 2022-12-15; most recent amendment 2026-03-25.
Status change: Recruiting → Active, Not Recruiting 2025-03-03
Status change: Suspended → Recruiting 2023-11-07
Status change: Recruiting → Suspended 2023-04-26
Status change: Not Yet Recruiting → Recruiting 2023-03-27
Trial Details
NCT Number NCT05662865
Lead Sponsor AdventHealth Translational Research Institute
Conditions Ketones, Metabolism
Enrollment 9 participants
Start Date 2023-03-16
Primary Completion 2024-07-23 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2026-03-30