Clinical Trial

NIMH K23: Modulation of Frontoparietal Dynamics in Adolescent Working Memory Deficits

Recruiting
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Summary
Working memory (WM) deficits are a transdiagnostic feature of adolescent psychopathology that substantially contribute to poor clinical and functional outcomes. This proposal will utilize a multimodal neuroscientific approach to investigate whether non-invasive brain stimulation can modulate the neural mechanisms underlying adolescent WM deficits. Directly in line with NIMH priorities, the researchers will identify the contributing roles of prefrontal and parietal regions in WM processes, as well as identify optimal targets and parameters for novel brain-based treatments in adolescent psychopathology. This study is funded by the NIMH-K23
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2022-12-15; most recent amendment 2026-04-27.
Status change: Active, Not Recruiting → Recruiting 2026-04-27
Status change: Recruiting → Active, Not Recruiting 2025-09-03
Trial Details
NCT Number NCT05662280
Lead Sponsor Bradley Hospital
Conditions Working Memory
Enrollment 40 participants
Start Date 2022-12-01
Primary Completion 2026-12-01 (estimated)
Study Completion 2026-12-01 (estimated)
Updated on ClinicalTrials.gov 2026-05-01