Follow up Study on Visual Prognosis and Complications of Ectopia Lentis Lens

This is a single-centre, observational cohort study with the following objectives: Firstly, the investigators aim to evaluate the vision-related quality of life and mental health status in congenital ectopia lentis patients. Secondly, the investigators target to investigate the correlations between genotype and clinical phenotype in patients of congenital ectopia lentis. Thirdly, to explore the metabolic profiles in the aqueous humor (AH) of patients with congenital ectopia lentis. Lastly, this study aims to explore the longitudinal changes of ocular biological parameters and complications in patients with postoperative congenital ectopia lens in the Chinese population.

NCT Number	NCT05654025
Lead Sponsor	Zhongshan Ophthalmic Center, Sun Yat-sen University
Conditions	Ectopia Lentis, Dislocation, Lens
Enrollment	604 participants
Start Date	2022-12-05
Primary Completion	2027-12 (estimated)
Study Completion	2027-12 (estimated)
Updated on ClinicalTrials.gov	2024-08-07