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Efficacy and Tolerance of Baricitinib, a JAK Inhibitor, in the Treatment of Refractory Non-infectious Non-anterior Uveitis

Study acronym: JAKUVEITE
StatusNot Yet Recruiting
PhasePhase 3
Started2026-07
View on ClinicalTrials.gov ↗

Amendment history

2026-06-05
notable
Study Status, Contacts/Locations v2
Primary completion pushed: 2029-08 → 2029-12
Completion pushed: 2029-08 → 2029-12
Start date2026-03→2026-07
Study sites0→1
2026-02-05
minor
Study Status v1
Primary completion date2023-08-01→2029-08
Completion date2026-08-01→2029-08
Start date2023-02-01→2026-03
2022-12-07
minor
Original filing
The aim of the study is to evaluate the efficacy of Baricitinib, a JAK1 and 2 inhibitor, in the management of non-infectious non-anterior uveitis refractory to at least one line of biotherapy (anti-TNF alpha, tocilizumab) after 6 months of treatment
Trial Details
NCT Number NCT05651880
Lead Sponsor University Hospital, Rouen
Conditions Active Non-anterior Non-infectious Uveitis
Enrollment 33 participants
Start Date 2026-07
Primary Completion 2029-12 (estimated)
Study Completion 2029-12 (estimated)
Updated on ClinicalTrials.gov 2026-06-08