Exercise to Improve Sleep in Parkinson's Disease

This study will investigate the impact of three common exercise modalities, cardiovascular, resistance, and multimodal (i.e., a combination of the previous two) training, on sleep quality and architecture in persons with Parkinson's disease (PD). Furthermore, the project will investigate whether the potential positive exercise-induced changes in sleep are associated with improvements in different quality of life (QoL)-related aspects. Participants will perform either cardiovascular training (CT), resistance training (RT), multimodal training (MT), or will be allocated to a control condition (i.e., waiting list - CON) for 12 weeks. Training will be performed three times/week. The assessments will be conducted at baseline, post-intervention, and follow-up (i.e. 8 weeks after the intervention) by assessors blinded to the participants' group allocation.

NCT Number	NCT05644327
Lead Sponsor	McGill University Collaborators: Jewish Rehabilitation Hospital, The Memory Lab, The Human Brain Control of Locomotion Lab (HBCL), The Cummings Centre, Canadian Institutes of Health Research (CIHR)
Conditions	Parkinson Disease
Enrollment	150 participants
Start Date	2021-09-01
Primary Completion	2027-12-30 (estimated)
Study Completion	2027-12-30 (estimated)
Updated on ClinicalTrials.gov	2026-03-13