Clinical Trial

Vaginal Microbiome and HPV Pre-malignant and Cervical Dysplasia

Recruiting
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Record status
This record was last updated March 19, 2025 (before its estimated December 30, 2025 completion). Its status may not reflect the trial's current state.
Summary
In this study, the investigators will prospectively collect, analyze and integrate information regarding vaginal microbiome composition and HPV presence in women with cervical pathologies (high-grade CIN and CC) and controls, to construct a large dataset from patients with pre-cancerous cervical lesions and healthy women, to evaluate the personalized contribution of the vaginal microbiome to the CIN-CC sequence.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2022-11-28; most recent amendment 2025-03-15.
Trial Details
NCT Number NCT05640700
Lead Sponsor Hadassah Medical Organization
Conditions Human Papilloma Virus, Vaginal Flora Imbalance, Cancer Cervix Uterus, Cervical Dysplasia
Enrollment 90 participants
Start Date 2022-11-09
Primary Completion 2025-12-30 (estimated)
Study Completion 2025-12-30 (estimated)
Updated on ClinicalTrials.gov 2025-03-19