Clinical Trial

NO AD: Use of Nitric Oxide (NO) Donors for the Prevention of Autonomic Dysreflexia (AD) During Bowel Care Following SCI

Study acronym: NO AD
Not Yet Recruiting Phase 2
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Summary
This project aims to evaluate the safety and efficacy of using a short-acting drug to reduce the maximal blood pressure during dangerous blood pressure spikes that happen during bowel care in individuals with spinal cord injury. the investigators will monitor the physiological effects of this drug during at-home bowel care to best understand the drug's effects in typical use.
Protocol Amendment History 4 amendments
This ClinicalTrials.gov record has been amended 4 times since 2022-11-30; most recent amendment 2026-04-22.
Trial Details
NCT Number NCT05635851
Lead Sponsor Simon Fraser University
Collaborators: University of British Columbia
Conditions Spinal Cord Injuries, Autonomic Dysreflexia
Enrollment 26 participants
Start Date 2026-12
Primary Completion 2028-02 (estimated)
Study Completion 2028-02 (estimated)
Updated on ClinicalTrials.gov 2026-04-23