Clinical Trial

Cognitive Remote Assessment Using FLAME (CRA-FLAME)

Enrolling by Invitation

Record status

This record was last updated May 31, 2025 (before its estimated December 1, 2025 completion). Its status may not reflect the trial's current state.

Summary

We aim to use a multimodal approach comprising conventional neuropsychological cognitive tests, fluid and imaging biomarker data, to explore their association with the FLAME unsupervised cognitive computerized assessment. We believe that this would provide critical information to move forward the current research framework in the field. Participants will be selected from BBRC-sponsored studies, such as the ALFA project (STUDY 45-65 FPM/2012), the ALFA+ cohort study (ALFA - FPM - 0311), the Beta-AARC study (β-AARC\_BBRC2020) or the BarcelonaBeta Dementia Prevention Research Clinic study (BBRC-DemPrev-2018)

Protocol Amendment History 3 amendments

This ClinicalTrials.gov record has been amended 3 times since 2022-11-17; most recent amendment 2025-05-27.

Trial Details

NCT Number	NCT05624632
Lead Sponsor	Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
Conditions	Cognitive Impairment
Enrollment	400 participants
Start Date	2022-12-01
Primary Completion	2025-12-01 (estimated)
Study Completion	2026-12-01 (estimated)
Updated on ClinicalTrials.gov	2025-05-31