Improving HIV Testing, Linkage, and Retention in Care for Men Through U=U Messaging

This study will evaluate the impact of U=U messaging and counseling on gaps in the HIV care cascade for men, including testing uptake and ART initiation (Aim 1), achieving viral suppression and retention in care (Aim 2) in two provinces in South Africa. The U=U message communicates the compelling idea that PLHIV who take ART and have an undetectable viral load (\<200 copies/mL) cannot sexually transmit HIV. Additionally, the investigators will conduct a multi-method evaluation to inform future implementation of U=U messaging interventions (Aim 3).

NCT Number	NCT05602376
Lead Sponsor	Desmond Tutu HIV Foundation Collaborators: National Institute of Mental Health (NIMH), National Institutes of Health (NIH), University of Pennsylvania
Conditions	HIV Infections, Men, Treatment Adherence
Enrollment	3,642 participants
Start Date	2023-03-31
Primary Completion	2026-12-31 (estimated)
Study Completion	2027-05-31 (estimated)
Updated on ClinicalTrials.gov	2024-11-01