Clinical Trial

Dose Escalation for SBRT of Recurrent VT Ventricular Tachyarrhythmia - a Single Center, Phase II Clinical Trial

Study acronym: DEFT STAR
Recruiting Phase 1
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Summary
The objective of this study is to demonstrate that higher radiation doses are necessary to induce transmural scar formation which is currently assumed to be the underlying mechanism of successful long-term efficacy of VT treatment and therefore dose-escalation will lead to a significantly reduced long-term VT recurrence rate compared to the currently applied single dose of 25 Gy.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2022-10-21; most recent amendment 2025-02-26.
Trial Details
NCT Number NCT05594368
Lead Sponsor University of Zurich
Conditions Ventricular Tachycardia
Enrollment 15 participants
Start Date 2022-07-01
Primary Completion 2027-12-31 (estimated)
Study Completion 2028-12-31 (estimated)
Updated on ClinicalTrials.gov 2025-03-03