Microparticles Blood Level in Acute Carbon Monoxide Poisoning

The goal of this pilot, clinical, experimental, biological and prospective study with uso of biological material (venous blood sampling), in patient with acute carbon monoxide (CO) intoxication and in a group of healthy non-intoxicated subject (group of control) is the research of a possible increase of circulating microparticles level in human blood with an acute carbon monoxide intoxication. The main question to answer is: Is there an increase of circulating microparticles levels in subjects with acute carbon monoxide poisoning? Two blood samples will be withdrawn from patients with acute carbon monoxide poisoning, one before and one after hyperbaric oxygen treatment. Researchers will compare a group of healthy volunteers to see if there is a different in circulating microparticles blood level compared to patients with intoxication.

NCT Number	NCT05591300
Lead Sponsor	Azienda Ospedaliero Universitaria Maggiore della Carita Collaborators: Università degli Studi del Piemonte Orientale Amedeo Avogadro
Conditions	Carbon Monoxide Poisoning
Enrollment	108 participants
Start Date	2022-11-15
Primary Completion	2025-04 (estimated)
Study Completion	2025-11 (estimated)
Updated on ClinicalTrials.gov	2024-11-14