Clinical Trial

ED2PrEP - Patient Focused, Low-burden Strategies for PrEP Uptake Among Emergency Departments

Study acronym: ED2PrEP
Active, Not Recruiting
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Summary
Severe inequities in HIV pre-exposure prophylaxis (PrEP) access and use in communities hardest hit by the HIV epidemic persist, further exacerbating ongoing racial/ethnic and socioeconomic disparities in HIV incidence. In these same communities, many patients at risk for HIV seek care for sexually transmitted infections (STIs) in Emergency Departments (EDs), but the structure of traditional ED care is poorly suited to address HIV prevention or provide PrEP. To advance the Prevent objective of the Ending the HIV Epidemic (EHE) initiative, ED2PrEP will leverage an implementation science approach to rigorously test two innovative strategies for increasing PrEP uptake among patients seeking STI care in EDs in one of the 48 EHE-identified geographic hotspots.
Protocol Amendment History 9 amendments
This ClinicalTrials.gov record has been amended 9 times since 2022-10-18; most recent amendment 2026-03-27.
Status change: Recruiting → Active, Not Recruiting 2026-03-13
Status change: Not Yet Recruiting → Recruiting 2024-04-11
Trial Details
NCT Number NCT05588193
Lead Sponsor Albert Einstein College of Medicine
Collaborators: National Institute of Allergy and Infectious Diseases (NIAID)
Conditions HIV
Enrollment 1,560 participants
Start Date 2024-10-01
Primary Completion 2026-02-13 (estimated)
Study Completion 2026-11-13 (estimated)
Updated on ClinicalTrials.gov 2026-03-31