Clinical Trial

E-field Guided iTBS for Treatment Resistant Depression

Recruiting
View on ClinicalTrials.gov →
Summary
The purpose of this study is to establish how personalization of repetitive transcranial magnetic stimulation (rTMS) can change markers of brain activity and improve treatment response. To do this, all participants will receive the same active form of treatments, but some of the participants in this study will receive intermittent theta burst stimulation (iTBS) rTMS treatment with standard forms of targeting and intensity, and others will receive iTBS rTMS treatment using personalized magnetic resonance imaging (MRI) and electric field (E-field) modeling measures.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2022-10-13.
Status change: Not Yet Recruiting → Recruiting 2023-09-25
Trial Details
NCT Number NCT05583747
Lead Sponsor Centre for Addiction and Mental Health
Collaborators: University Health Network, Toronto
Conditions Major Depressive Disorder
Enrollment 110 participants
Start Date 2022-10-24
Primary Completion 2027-03-31 (estimated)
Study Completion 2027-07-31 (estimated)
Updated on ClinicalTrials.gov 2023-09-26