Clinical Trial

Collagen Matrix + rhPDGF-BB vs Connective Tissue Graft for the Treatment of Peri-implant Soft Tissue Dehiscences

Active, Not Recruiting
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Record status
This record was last updated April 10, 2025 (before its estimated October 20, 2025 completion). Its status may not reflect the trial's current state.
Summary
The study aims at comparing two different approaches for the treatment of implant esthetic complications (peri-implant soft tissue dehiscences): autogenous connective tissue graft vs collagen matrix + recombinant human platelet derived growth factor-BB
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2022-10-08; most recent amendment 2025-04-08.
Status change: Recruiting → Active, Not Recruiting 2025-01-28
Status change: Not Yet Recruiting → Recruiting 2023-01-04
Trial Details
NCT Number NCT05576922
Lead Sponsor Harvard Medical School (HMS and HSDM)
Conditions Implant Complication
Enrollment 28 participants
Start Date 2023-01-04
Primary Completion 2025-10-20 (estimated)
Study Completion 2025-10-21 (estimated)
Updated on ClinicalTrials.gov 2025-04-10