Clinical Trial

Intercorporal Bone Graft Measurement Study

Active, Not Recruiting
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Summary
Instrumented lumbar fusion surgery is often accompanied by interbody fusion using an autologous bone graft that is supposed to expand and remodel to achieve a rigid and lasting bony construction between two vertebrae. However, there is a dearth of knowledge regarding the process of biological remodelling of intercorporal bone grafts. Also, a valid and reliable assessment of fusion status remains challenging because there is no objective tool available to quantify the bone remodelling process. CT-based Hounsfield Units correlate with Bone Mineral Density and can be used as a proxy to establish trajectories over time to assess changes in bone mineral density from the bone graft.
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2022-09-29; most recent amendment 2026-06-22.
Status change: Recruiting → Active, Not Recruiting 2025-08-04
Status change: Not Yet Recruiting → Recruiting 2022-12-12
Trial Details
NCT Number NCT05565456
Lead Sponsor Rijnstate Hospital
Conditions Spondylolisthesis, Spinal Fusion
Enrollment 30 participants
Start Date 2022-12-02
Primary Completion 2026-11-01 (estimated)
Study Completion 2026-11-01 (estimated)
Updated on ClinicalTrials.gov 2026-06-25