@neurIST : Intregrated Biomedical Informatics for the Management of Cerebral Aneurysms

The primary aim of the SwissNeuroFoundation AneurysmDataBase Project is to implement information technology based tools to create and use a holistic reference database specific to intracranial aneurysms (IA). The SwissNeuroFoundation AneurysmDataBase are concerned with generating the data with which to populate this database. The purpose for populating the database are to: * Screen for and evaluate markers of risk for intracranial aneurysm formation and aneurysm rupture. Are considered as markers the following: genetics factors, microbiota, environmental factors, congenital factors (ie: cerebrovascular anatomical variants), transcriptomics signature, proteomics signature,shape characteristics, haemodynamics characteristics. * Screen for and evaluate prognostic factors of outcome regarding different management strategies including watchful observation, microsurgical treatment, endovascular treatment or any combination thereof. * Implement and evaluate patient-specific management protocols integrating all available information. * Evaluate the impact of the database and use of tools to improve care, reduce costs, support knowledge discovery and promote new industrial developments.

NCT Number	NCT05526352
Lead Sponsor	University Hospital, Geneva Collaborators: University of Geneva, Switzerland, Klinik Hirslanden, Zurich
Conditions	Intracranial Aneurysm
Enrollment	20,000 participants
Start Date	2015-06-01
Primary Completion	2040-03-01 (estimated)
Study Completion	2040-03-01 (estimated)
Updated on ClinicalTrials.gov	2026-01-16