Clinical Trial

Doxycycline in Cutaneous Schwannoma (NF2)

Active, Not Recruiting Phase 1/2
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Summary
In this research study the investigators want to learn more about an alternate, local treatment for skin schwannomas. Specifically, local doxycycline intra-tumoral injection will be performed as a potential treatment for NF2-related skin schwannomas, ultimately reducing the risks and costs associated with standard surgical removal of such skin tumors if successful.
Protocol Amendment History 6 amendments
This ClinicalTrials.gov record has been amended 6 times since 2022-08-26; most recent amendment 2025-12-01.
Status change: Recruiting → Active, Not Recruiting 2025-12-01
Trial Details
NCT Number NCT05521048
Lead Sponsor Massachusetts Eye and Ear Infirmary
Conditions Neurofibromatosis Type 2
Enrollment 19 participants
Start Date 2022-09-19
Primary Completion 2026-09-01 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2025-12-08