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NCT05517811 · ClinicalTrials.gov record · last posted 2026-08-24

Pre- and Post-operative TEG Indices in Patients With or Without Adenocarcinoma Undergoing Surgical Resection

Study acronym: TEG
StatusRecruiting
PhaseNot specified
Started2022-06-26
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from the ClinicalTrials.gov record
The investigators hypothesize that abnormalities in thromboelastography (TEG) parameters in patients with liver, pancreas, biliary, esophageal, colorectal, and lung adenocarcinoma can serve as biomarkers for oncologic disease burden, cancer recurrence and overall survival as well as thrombotic and hemorrhagic post-operative complications. The investigators further hypothesize that there is histologic pathology correlates to pre-operative TEG abnormalities, and that it identifies patients with virulent tumor biology.

Protocol amendment history 1 change detected by DataLookout

2026-08-25
critical
Enrollment reduced: 400 → 200 participants
Trial Details
NCT Number NCT05517811
Lead Sponsor University of Colorado, Denver
Collaborators: Haemonetics Corporation
Conditions Liver Cancer, Esophageal Cancer, Colorectal Cancer, Lung Adenocarcinoma, Control, Pancreas Cancer, Biliary Cancer
Enrollment 200 participants
Start Date 2022-06-26
Primary Completion 2028-05-31 (estimated)
Study Completion 2028-07-31 (estimated)
Updated on ClinicalTrials.gov 2026-08-24